解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
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生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::The purpose of this study was to determine the dietary essentiality of lithium (Li) in rats. In three experiments, two types of diets were fed during growth, reproduction, and lactation. In the first experiment, dams were maintained on a corn-based diet containing 2 ng or 500 ng (controls) Li/g through five successive...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783685
更新日期:1992-09-01 00:00:00
abstract::Divalent metal ions (Fe2+, Cu2+, Zn2+, Ni2+, and Mn2+) induced lipid oxidation in cooked, but not in raw fish. The extent of lipid oxidation, measured by the production of thiobarbituric acid reactive substances (TBRS), was increased with higher concentrations of iron, zinc, and nickel, but was decreased with increasi...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02783896
更新日期:1992-07-01 00:00:00
abstract::With reports of either no change or reduction of blood pressure, the relationship between selenium and blood pressure has not been clear. Normal Se values are not available for the Sprague Dawley (SD) rat or in the young and adult rat with various models of experimental hypertension. This study measured serum Se level...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784001
更新日期:1992-04-01 00:00:00
abstract::Selenium is increasingly recognized as a versatile anticarcinogenic agent. Its protective functions cannot be solely attributed to the action of glutathione peroxidase. Instead, selenium appears to operate by several mechanisms, depending on dosage and chemical form of selenium and the nature of the carcinogenic stres...
journal_title:Biological trace element research
pub_type: 杂志文章,评审
doi:10.1007/BF02783992
更新日期:1992-04-01 00:00:00
abstract::A simple, quick procedure has been developed for preparation of human lenses for total chromium (Cr) analysis by electrothermal atomic absorption spectrometry (EAAS). This procedure involves wet ashing in a mini-autoclave with HNO3 and H2SO4. Recovery was 101.6%. This procedure is simple to carry out, does not generat...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784598
更新日期:1992-01-01 00:00:00
abstract::A survey based on 838 samples of milk obtained from 537 dairies covering 70 of 95 districts in France was organized to assess iodine content of milk and its contribution to total intake. Iodine levels were significantly higher in winter than in summer. Very low iodine contents (less than 25 micrograms I/kg) were found...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784607
更新日期:1992-01-01 00:00:00
abstract::Many studies have shown that zinc deficiency could decrease the response to insulin. In genetically diabetic animals, a low zinc status has been observed contrary to induced diabetic animals. The zinc status of human patients depends on the type of diabetes and the age. Zinc supplementation seems to have beneficial ef...
journal_title:Biological trace element research
pub_type: 杂志文章,评审
doi:10.1007/BF02784615
更新日期:1992-01-01 00:00:00
abstract::The characteristics of aluminum and chromium binding to apo-transferrin (apo-tf) have been investigated and compared. Both metal ions were taken up by human transferrin forming complexes with the maximum absorbances at 405 nm for chromium-transferrin (cr-tf) and 240 nm for aluminum-transferrin (Al-tf). In the presence...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784585
更新日期:1992-01-01 00:00:00
abstract::Several authors have already underlined chromium implication in glucose and lipids metabolism of humans. In this field, physiological chromium determination in serum could be helpful, but the discrepancies reported in numerous papers are confusing. Here we report some results obtained by Zeeman correction Graphite Fur...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02784591
更新日期:1992-01-01 00:00:00
abstract::Serum copper and zinc estimations in humans were made to find their diagnostic and prognostic value in cases of myocardial infarction. Following infarction, there was an increase in serum copper levels from the first 24 h up to the 7th day, with gradual decline that did not reach the normal value up to the 14th day. T...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990200
更新日期:1991-12-01 00:00:00
abstract::The phosphorus NMR profile of normal and vanadium-treated chick muscle was obtained in vivo. The data show that the differentiation of breast and thigh muscles in terms of pH, lipid related metabolites, and bioenergetic parameters can be readily followed. Although the vanadium-treated chicks showed substantial retarda...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990427
更新日期:1991-11-01 00:00:00
abstract::In 47 children with malignancy, zinc status, growth, and performance during standard treatment were compared with those in controls. At diagnosis, growth was retarded and hair zinc values were high, 2.4 +/- 0.7 mumol/g, as in chronic deficiency. During induction therapy, serum declined to 10.4 +/- 2.3 mumol/L and urin...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02991414
更新日期:1991-09-01 00:00:00
abstract::Intraperitoneal administration of zinc chloride (ZnCl2) to Swiss albino mice in vivo induced a significant (p less than or equal to 0.05) increase in the frequencies of chromosomal aberrations of the bone-marrow cells at all concentrations used following acute (7.5, 10, 15 mg/kg body weight) and chronic (2.0, 3.0 mg/k...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990346
更新日期:1991-08-01 00:00:00
abstract::The effect of low copper and high zinc intakes on Cu,Zn-superoxide dismutase (Cu,Zn-SOD) activity and mammary tumorigenesis induced by 9,10-dimethyl-1,2-benzanthracene (DMBA) was investigated. Groups of 40 weanling female Sprague-Dawley rats were fed a modified AIN-76 diet containing the following (/kg diet): 1 mg Cu ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990343
更新日期:1991-07-01 00:00:00
abstract::Contents of Cu and Zn of into-pulmonary blood (IPB), out-pulmonary blood (OPB), Lung tissue, and supernatant and macrophages of Lung Lavage were determined in superior mesenteric artery occlusion (SMAO) shock of rabbits. Zn of pulmonary tissue was 11.42 +/- 0.60 and 14.52 +/- 1.78 (micrograms/g wet wt) in SMAO shock a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF03032684
更新日期:1991-06-01 00:00:00
abstract::The effects of cobaltous chloride in inducing chromosomal aberrations were observed on laboratory bred mice in vivo after single oral administration of different fractions (1/10, 1/20, 1/40) of the lethal toxic dose of the salt. Bone marrow cells were flushed out and processed for chromosome studies following colchici...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF03032691
更新日期:1991-05-01 00:00:00
abstract::This study was undertaken to evaluate a systematic analysis of mineral and trace elements of individual functionally determined parts of adult temporal bone. Marked differences were observed in basic structural elements (Ca, P, Mg, and Zn) among different bone regions. The more so, molar Ca/P ratio was significantly d...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF03032672
更新日期:1991-04-01 00:00:00
abstract::Aspergillus terreus was cultivated on Harrold's medium supplemented with 0.1% (w/v) cadmium chloride as well as on sulfur free medium amended with 0.1% (w/v) sodium selenite and potassium tellurite separately. The cell free extract of the fungus for each treatment was fractionated on a column packed with Sephadex G 75...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990464
更新日期:1991-03-01 00:00:00
abstract::Cadmium concentrations were determined in the hair of 226 school children in an industrial and in a rural area of Tarragona Province (NE Spain). The influence of sex, age, hair color, smoking habits of the household members, and parents' occupation on the children's hair cadmium levels was also evaluated. Children liv...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02863080
更新日期:1991-02-01 00:00:00
abstract::Selenomethionine metabolism and the biochemical basis for its cytotoxicity were analyzed in cultured human and murine lymphoid cells. The metabolic pathways were also addressed, using purified mammalian enzymes and crude tissue extracts. Selenomethionine was found to be effectively metabolized to S-adenosylmethionine ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990463
更新日期:1991-01-01 00:00:00
abstract::A double label procedure with 57Co and 58Co has been developed for detailed in vivo studies of erythrocyte survival. A well-type Ge detector is used in the measurements. The activities necessary for these experiments are very low, and the associated dose received by the test persons can be neglected. ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992664
更新日期:1990-07-01 00:00:00
abstract::Multivariate statistical analysis has been applied to time series measurements of aerosol elemental composition from PIXE analysis of filter samples, and principal components have been resolved that represent distinct particle types in an external mixture in the atmosphere. In this study, it is argued that a combinati...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992673
更新日期:1990-07-01 00:00:00
abstract::X-ray Fluorescence (XRF) Analysis and Atomic Absorption Spectrophotometry (AAS) have been used in assessing heavy metal pollution from some gold mines in Ghana. The presence and levels of heavy metals in gold ore, gold tailings, inland waters, and river sediments have been determined. Using these techniques, the heavy...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992682
更新日期:1990-07-01 00:00:00
abstract::Multielemental detection using Instrumental Neutron Activation Analysis (INAA) and Proton-Induced X-Ray Emission (PIXE) of drinkable water of Florence (Italy) is described. The concentrations of 52 elements were measured. No chemical treatment was performed on the samples, before or after irradiation. On the basis of ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992691
更新日期:1990-07-01 00:00:00
abstract::This work is a first attempt to determine the speciation of Cr in human plasma. With the aid of in vitro and in vivo 51Cr-labeled experiments, it was possible to develop the necessary biochemical techniques for the separation of the plasma proteins. Further work will use real samples, taking care to avoid contaminatio...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992700
更新日期:1990-07-01 00:00:00
abstract::A microcomputer-controlled irradiation and measurement system and a microprocessor-controlled sample changer have been installed at the SLOWPOKE-2 Facility at the Royal Military College of Canada (RMC). These systems can provide the gamut of instrumental neutron activation analysis (INAA) techniques for the analyst. C...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992658
更新日期:1990-07-01 00:00:00
abstract::A rapid cyclic instrumental neutron activation analysis (CINAA) method has been used to determine the selenium content of 27 duplicate diet samples from each of the 27 districts surrounding Pinhel, Portugal. The accuracy and precision of the CINAA method have been evaluated by analyzing certified reference materials a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992719
更新日期:1990-07-01 00:00:00
abstract::Variations in trace element concentration in the head and facial hair of five individuals with ever-increasing amounts of white hair were examined. Hair was collected from the scalp, cheeks, and chin from one donor on a regular basis since 1984. Samples were separated into white and pigmented fractions, and analyzed a...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992728
更新日期:1990-07-01 00:00:00
abstract::Elemental analysis of archaeological bones, particularly for elements such as fluorine, strontium, and zinc, has been carried out for many years, with the aim of determining their age or relating their composition to diet. Bone samples are commonly dry ashed before analysis to remove organic material and render them m...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990417
更新日期:1990-06-01 00:00:00
abstract::Sponge granuloma formation was compared in copper-deficient and copper-sufficient rats following feeding of respective diets for 20, 40, or 60 d. Body weight, total blood hemoglobin, and activities of ceruloplasmin and Cu, Zn-superoxide dismutase in plasma were monitored to ascertain copper deficiency. Mean granuloma ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990272
更新日期:1990-05-01 00:00:00
abstract::In vitro distribution of aluminium between plasma and erythrocytes has been studied in the presence of variable amounts of sodium L-glutamate. With a red blood cell suspension in isotonic sodium chloride, aluminium remains confined in erythrocytes even when the sodium L-glutamate concentration increases in the medium....
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990262
更新日期:1990-04-01 00:00:00
abstract::The efficacy of selenate and other divalent anions to stimulate the efflux of radiolabeled sulfate from lactating rat mammary tissue slices has been examined. Both selenate and sulfate markedly increased the fractional release of sulfate via a system that is temperature-sensitive and sensitive to the anion-exchange in...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917205
更新日期:1990-03-01 00:00:00
abstract::The liver of Hooded Seal (Cystophora cristata) consists of six lobes of unequal sizes. Extensive sampling by means of cutout samples covering the depth horizon 2-30 mm below liver surface indicates that the liver may be considered homogeneous as to concentrations of zinc, cadmium, mercury, and selenium (residuals of o...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02789141
更新日期:1990-01-01 00:00:00
abstract::Atomic absorption spectrometry was used in a quantitative study of zinc, magnesium, and manganese on 71 postmortal human aortas. Samples were obtained from accident victims 35-65 years of age. Fibrous plaques had higher levels of all three elements when compared to normal aortic tissue. The difference was significant ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02916613
更新日期:1989-12-01 00:00:00
abstract::The metabolic effects of dietary boron, magnesium, and molybdenum on mineral metabolism in the cholecalciferol-deficient chick, with emphasis on growth cartilage histology, were studied. One-day-old cockerel chicks were assigned to groups in a fully-crossed, three factor, 2 x 2 x 2 design. The basal diet was based on ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02916650
更新日期:1989-11-01 00:00:00
abstract::Renal functions were damaged at the reabsorptive site by the injection of cadmium-metallothionein (Cd-MT) and its effect on discrimination of chemically similar elements was examined for the two alkaline-earth elements, calcium (Ca) and strontium (Sr). Tubular damage was induced in female Wistar rats, 7 wk old, body w...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917418
更新日期:1989-10-01 00:00:00
abstract::The glutathione transferase (GST) activity of rat liver cytosolic preparations with ethacrynic acid (EA) and (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydro-benzo(a)pyrene (BPDE) as substrates, increased by 125 and 350%, respectively, in animals that had been treated with a single intraveno...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917265
更新日期:1989-07-01 00:00:00
abstract::The effect of certain inorganic and coordinated nickel compounds on the resistance to different destructive substances, rheological properties, and functional activity of healthy human red blood cells (RBC), was investigated. It is shown that nickel compounds affect the erythrocyte membrane lipid bilayer, as well as m...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917273
更新日期:1989-07-01 00:00:00
abstract::Since chromium(VI) is unreactive toward DNA under physiological conditions in vitro, the ability of carcinogenic chromium(VI) compounds to damage DNA depends on the presence of cellular redox components that reduce chromium(VI) to reactive species capable of interacting with DNA. We have examined the role of glutathio...
journal_title:Biological trace element research
pub_type: 杂志文章,评审
doi:10.1007/BF02917282
更新日期:1989-07-01 00:00:00
abstract::In the mouse embryo cell line BALB/3T3 Clone A31-1-1, dose-dependent morphologic neoplastic transformation was obtained with NaAsO2, Na2HAsO4, CdCl2, and K2CrO4. Cellular uptake was four fold higher for As3+ than for As5+, and As5- was metabolized to As3+ in cytosol. Cytotoxicity and transformation rates were four fol...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02917291
更新日期:1989-07-01 00:00:00